Tumor suppression using placental stem cells
AssigneeAnthrogenesis Corporation
InventorsCasper Paludan, James W. Edinger, Ryhor Harbacheuski, RoseAnn Murray, Robert J. Hariri, Qian Ye
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Abstract
The present invention provides methods of suppression of tumor cell proliferation and tumor growth using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of tumor suppression, and compositions comprising such cells and cell populations.
Claims25
A method of suppressing the proliferation of a plurality of tumor cells comprising contacting said plurality of tumor cells with a plurality of adherent CD34−, CD10+, CD105+, CD200+ placental stem cells for a time sufficient for said placental stem cells to suppress proliferation of said plurality of tumor cells, as compared to a plurality of said tumor cells not contacted with placental stem cells, wherein said tumor cells are histiocytic lymphoma cells, chronic myelogenous leukemia cells, acute T-cell leukemia cells, acute myelogenous leukemia cells, colon adenocarcinoma cells, retinoblastoma cells or lung carcinoma cells.
Dependencies are inferred from the claim text.