System and method for determining an abused sensor during analyte measurement
AssigneesRoche Diagnostics Operations, Inc., Roche Operations Ltd.
InventorsDavid W. Burke, Lance S. Kuhn, James Maxwell
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Abstract
A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the corrected DC response. Other methods and devices are disclosed.
Claims12
A method for detecting an abused sensor for determining a concentration of a medically significant component of a biological fluid placed upon the sensor, comprising the steps of:
- a) placing the biological fluid sample upon the sensor;
- b) applying a first signal to the biological fluid;
- c) measuring a current response to the first signal;
- d) repeating step (c) at least once;
- e) calculating a normalized Cottrell Failsafe Ratio using the current response data;
- f) applying a second signal having an AC component to the biological fluid;
- g) measuring an AC response to the second signal;
- and
- h) combining the normalized Cottrell Failsafe Ratio and the AC response to produce an indication of whether the sensor has been abused.
A method of determining a failure condition indicating an abused sensor in a blood glucose concentration test, comprising the steps of:
- a) applying a first test signal having an AC component to a test sample;
- b) measuring a first phase angle response to the first test signal;
- c) applying a second test signal having an AC component to the test sample;
- d) measuring a second phase angle response to the second test signal;
- and
- e) determining a failure condition value based upon the first phase angle response the second phase angle response and a predetermined Cottrell Failsafe Ratio.
Dependencies are inferred from the claim text.