KIF11 and method for diagnosing non-small cell lung cancer
AssigneeOncotherapy Science, Inc.
InventorsYusuke Nakamura, Yataro Daigo, Shuichi Nakatsuru
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Abstract
Disclosed are methods for detecting non-small cell lung cancer (NSCLC) using differentially expressed genes KIF11, GHSR1b, NTSR1, and FOXM1. Also disclosed are methods of identifying compounds for treating and preventing NSCLC, based on the interaction between KOC1 and KIF11, or NMU and GHSR1b or NTSR1.
Claims7
A method of diagnosing non-small cell lung cancer (NSCLC) in a subject, comprising determining the expression level of KIF11 in a lung tissue sample derived from the subject, wherein an increase of said expression level compared to a normal control level of said gene indicates that said subject suffers from NSCLC.
A method of predicting an NSCLC prognosis, wherein the method comprises the steps of:
- (a) detecting the expression level of KIF11 in an NSCLC tissue collected from a subject diagnosed with NSCLC, and
- (b) indicating a poor prognosis when an elevation of the expression level of KIF11 is detected.
Dependencies are inferred from the claim text.