Method for imaging acoustically induced rotary saturation with a magnetic resonance imaging system

Abstract

A method for producing a magnetic resonance image indicative of mechanical waves applied to a subject is provided. Mechanical waves are applied to the subject at a selected frequency to induce oscillatory motion in tissues within the subject at the same frequency. A spin-lock radiofrequency pulse, having a resonance frequency matched to that of the induced oscillatory motion, is applied to the subject. This results in a spin-lock condition, during which transverse magnetization experiences rotary saturation resulting from magnetic field fluctuations produced by the oscillatory motion. Image data is acquired from the saturated transverse magnetization and images are reconstructed. As a result of the rotary saturation, these images exhibit darkening in those voxel locations affected by the oscillatory motion. In this manner, an image indicative of the applied mechanical waves is produced.

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