Modulators of ATP-binding cassette transporters
AssigneeVertex Pharmaceuticals Incorporated
InventorsSara S. Hadida Ruah, Matthew Hamilton, Mark Miller, Peter D. J. Grootenhuis, Brian Bear, Jason McCartney, Jinglan Zhou, Fredrick van Goor
Life of this patent
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Abstract
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
Claims1
A method of treating or lessening the severity of cystic fibrosis in a patient, comprising the step of administering to said patient an effective amount of a compound selected from the following
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Dependencies are inferred from the claim text.