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US 7,951,841 B2Granted
Retinal derivatives and methods for the use thereof for the treatment of visual disorders
AssigneeUniversity of Washington
InventorsKrzysztof Palczewski, Matthew Batten
Life of this patent
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Abstract
Compositions of and methods for using synthetic retinal derivatives as retinoid replacements and opsin agonists are provided.
Claims18
A method of restoring photoreceptor function in a human eye, the method comprising
- administering an effective amount of a synthetic retinal derivative to a human subject with an endogenous 11-cis-retinal deficiency,
- wherein the synthetic retinal derivative is 9-cis-retinyl acetate.
A method of ameliorating loss of photoreceptor function in a human subject with an endogenous 11-cis-retinal deficiency, the method comprising:
- administering an effective amount of a synthetic retinal derivative to the human subject,
- wherein the synthetic retinal derivative is 9-cis-retinyl acetate.
Dependencies are inferred from the claim text.