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AssigneesBoard of Trutees of the University of Arkansas, The United States of America as represented by the Secretary of Agriculture
InventorsBilly M. Hargis, Stacy E. Higgins, Lisa Bielke, Guillermo I. Tellez, Lisa A. Newberry, Gerardo Nava, Ann M. Donoghue, Daniel J. Donoghue
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Disclosed are methods of selecting wide host range bacteriophage capable of growing in a plurality of bacteria including pathogenic and non-pathogenic bacteria and bacteriophage selected by the methods. Also disclosed are methods of treating a subject infected with a pathogenic bacterium using bacteriophage and methods of decontaminating objects using bacteriophage. Also disclosed are methods of producing vaccines. In another aspect, methods of determining bacterial viability and methods of improving the sensitivity of a biosensor using wide host range bacteriophages are disclosed.
A method of reducing bacterial contamination of a food product comprising applying a composition comprising at least one wild-type wide host range bacteriophage prepared by passage in a non-pathogenic bacterium to the food product, the bacteriophage capable of lysing a bacterium contaminating the food product, wherein the wide host range bacteriophage is capable of infecting more than one genus of bacteria.
A method of reducing bacterial contamination of a food product, comprising:
Dependencies are inferred from the claim text.