Sinus delivery of sustained release therapeutics
AssigneeIntersect ENT, Inc.
InventorsDonald J. Eaton, Mary Lynn Moran, Rodney A. Brenneman
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Abstract
The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
Claims17
A method for treating a sinus condition comprising:
- accessing a paranasal sinus cavity with a delivery device loaded with a plurality of biodegradable implants;
- activating the delivery device to a first configuration to deliver a first of the plurality of biodegradable implants to the paranasal sinus cavity;
- and
- subsequently activating the delivery device to a second configuration to deliver a second of the plurality of biodegradable implants to the paranasal sinus cavity,
- wherein the first biodegradable implant comprises an active agent.
Dependencies are inferred from the claim text.