Devices, systems and methods for medicament delivery

An apparatus, comprising:

• a housing defining a gas chamber;
• a medicament container movably disposed within the housing;
• a medicament injector configured to be movably disposed within the housing, the medicament injector including a carrier and a movable member, the carrier including a valve actuator, the movable member having a first end portion and a second end portion, the first end portion defining a portion of a boundary of the gas chamber, the first end portion including a seal configured to engage a portion of the housing to fluidically isolate the gas chamber from an area outside the gas chamber, the second end portion being disposed within the medicament container;
• an injection member configured to be coupled to the carrier, the injection member defining a lumen configured to be in fluid communication with the medicament container, the injection member configured to convey a medicament from the medicament container into a body of a patient,
• the medicament injector having a first position and a second position, in the first position the injection member is contained within the housing, in the second position a portion of the injection member extends from the housing,
• the movable member configured to move relative to the carrier between a first movable member position and a second movable member position to expel a medicament contained within the medicament container via the injection member;
• and
• a valve disposed on the first end portion of the movable member, the valve having a first configuration and a second configuration, in the first configuration, the gas chamber is fluidically isolated from the area outside the gas chamber, in the second configuration the gas chamber is in fluid communication with the area outside the gas chamber,
• the valve actuator is configured to engage the valve when the movable member is in the second movable member position.

An apparatus, comprising:

• a housing defining a gas chamber;
• a movable member having a first portion and a second portion, the first portion defining a portion of a boundary of the gas chamber, the second portion configured to be coupled to a needle configured to deliver a medicament, the movable member configured to be disposed within the housing in a first position and a second position, in the first position the needle is disposed within the housing, in the second position a portion of the needle extends outside the housing;
• and
• a gas release member having a first configuration and a second configuration, when the gas release member is in the first configuration the gas chamber is fluidically isolated from an area outside the gas chamber, when the gas release member is in the second configuration the gas chamber is in fluid communication with the area outside the gas chamber,
• the gas release member configured to be moved from its first configuration to its second configuration when the movable member is in its second position, the gas release member configured to be maintained in its second configuration when the movable member moves back from its second position towards its first position.

An apparatus, comprising:

• a housing defining a gas chamber;
• a movable member configured to move within the housing, the movable member having a first portion and a second portion, the first portion defining a portion of a boundary of the gas chamber, the second portion configured to move a plunger within a medicament container to expel a medicament contained within the medicament container when the movable member moves within the housing;
• and
• a valve coupled to the first portion of the movable member, the valve fluidically isolating the gas chamber and an area outside the gas chamber when the movable member moves within the housing to expel the medicament, the valve configured to be placed in an opened configuration such that the gas chamber is in fluid communication with the area outside the gas chamber after at least a portion of the medicament has been expelled.

An apparatus, comprising:

• a carrier configured to be disposed within a housing of a medical device, a first end portion of the carrier configured to be coupled to a medicament container, a second end portion of the carrier including a valve actuator;
• a movable member configured to move relative to the carrier, the movable member having a first end portion and second end portion, a portion of the first end portion configured to define a portion of a boundary of a gas chamber, the first end portion defining an opening configured to be in fluid communication between the gas chamber and an area outside the gas chamber, the movable member includes a sealing portion configured to engage a portion of the housing to fluidically isolate the gas chamber from the area outside the gas chamber, the second end portion configured to be engaged with the medicament container;
• and
• a valve coupled to the movable member, the valve configured to allow fluid communication between the gas chamber and the area outside the gas chamber through the opening defined by the first end portion when the valve is actuated by the valve actuator of the carrier.