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US 7,943,312 B2Granted
Enzyme treatment of foodstuffs for celiac sprue
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsFelix Hausch, Gary Gray, Lu Shan, Chaitan Khosla
Life of this patent
Estimating the term…
Abstract
Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.
Claims17
A method of degrading gluten in a foodstuff ingested by an individual, the method comprising:
- orally administering to said individual a glutenase with ingestion of said foodstuff by said individual in an amount effective to cleave in vivo an ingested gluten oligopeptide having the amino acid sequence of SEQ ID NO:12;
- wherein said glutenase degrades said gluten in said foodstuff to fragments shorter than 8 amino acids in said individual.
Dependencies are inferred from the claim text.