Chondroitin sulfate synthesis promoter
AssigneesTokyo Medical and Dental University, Seikagaku Corporation
InventorsKenichiro Sakai, Koji Kimata, Kenichi Shinomiya, Hideto Watanabe
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Abstract
The invention provides a chondroitin sulfate synthesis promoter useful for the treatment of diseases such as articular disease and discopathy. The chondroitin sulfate synthesis promoter contains, as an active ingredient, chondroitin sulfate glucuronyltransferase protein and/or chondroitin sulfate N-acetylgalactosaminyltransferase-1 protein, or a gene encoding the enzyme protein(s).
Claims4
A method for promoting chondroitin sulfate synthesis in a living subject wherein the living subject is a joint, a cartilage, or an intervertebral disc, the method comprising the steps of:
- providing a nucleic acid encoding chondroitin sulfate N-acetylgalactosaminyltransferase-1 and having a nucleotide sequence defined by SEQ. ID NO:
- 3;
- and
- introducing the nucleic acid into the living subject.
Dependencies are inferred from the claim text.