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US 7,935,492 B2Granted
Goodpasture antigen binding protein and its detection
AssigneeFibrostatin, Sociedad Limitada
InventorsJuan Saus, Fernando Revert
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Abstract
The present invention provides native Goodpasture antigen binding protein isoforms, monoclonal antibodies directed against such proteins, and methods for their use.
Claims13
A method for detecting circulating 77 kD Goodpasture antigen binding protein (GPBP), comprising
- (a) contacting a plasma sample with an antibody that binds to 77 kD GPBP as set forth in SEQ ID NO:4 under conditions to promote selective binding of the antibody to the 77 kD GPBP;
- (b) removing unbound plasma and/or antibody;
- and
- (c) detecting complex formation between the antibody and the 77 kD GPBP in the plasma sample.
1 more element
Dependencies are inferred from the claim text.