Amine-based compound and use thereof

A compound represented by the following general formula (1) or a pharmacologically acceptable salt thereof:

• wherein
• n1, n2, and n3 represent an integer of 1;
• R1, R2, R3, R4, R5, and R6 each independently represent a hydrogen atom;
• Al and A2, each independently represent a hydrogen atom, a substitutable monocyclic or polycyclic heteroaromatic ring, a partly saturated substitutable polycyclic heteroaromatic ring, a substitutable monocyclic or polycyclic aromatic ring, a partially saturated substitutable polycyclic aromatic ring, a substitutable heteroring, or a group represented by the following formula (2):
• wherein
• R7, R8, R9, and R10 each independently represent a hydrogen atom, a substitutable alkyl group having 1 to 15 carbon atoms, a substitutable alkenyl group having 2 to 15 carbon atoms, a substitutable alkynyl group having 2 to 15 carbon atoms, or a substitutable cyclic alkyl group having 3 to 15 carbon atoms;
• W represents a phenyl group;
• X represents CH2;
• D represents a group represented by the following formula (6):
• —Q—Y—B (6)
• wherein
• Q represents NR12, wherein R12 represents —CH2)mCOOR36, wherein m represents an integer of 1 or 2 and R36 represents a hydrogen atom or an alkyl group having 1 to 5 carbon atoms;
• Y represents —(CH2)m3— wherein m3 represents an integer of 0 to 6;
• and
• B represents NR25R26wherein R25 and R26 each independently represent a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a cyclic alkyl group having 3 to 6 carbon atoms.