Fungal phytotoxin fusicoccin for the treatment and diagnosis of coagulation-correlated pathologies
AssigneeUniversita'Degli Studi Roma “Tor Vergata”
InventorsPatrizia Aducci, Lorenzo Camoni, Cristina Di Lucente, Sabina Visconti
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Abstract
The present invention concerns the use of tricyclic terpenes chosen from the group consisting of fusicoccin, ophyobolins or cotylenins for the therapy and diagnosis of coagulation-correlated pathologies such as Bernard-Soulier syndrome (BSS), von Willebrand disease (vWD), Glanzmann's thrombasthenia or thrombocytopenia.
Claims5
A method for treating coagulation-correlated pathologies comprising administering a therapeutically effective amount of at least one tricyclic terpenes chosen from the group consisting of fusicoccin, ophyobolins or cotylenins to a subject in need of such treatment.
A method for diagnosing coagulation-correlated pathologies comprising contacting a sample with at least one tricyclic terpenes chosen from the group consisting of fusicoccin, ophybolins or cotylenins in vitro.
Dependencies are inferred from the claim text.