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US 7,923,570 B2Granted
Process for the preparation of crystalline perindopril
AssigneeLek Pharmaceuticals D.D.
InventorsBranko Jenko, Anton Copar
Life of this patent
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Abstract
The present invention relates to a new process for the preparation of crystalline perindopril. The present invention also relates to new alkyl ammonium salts of perindopril and the processes for the preparation thereof.
Claims3
The tert-Octylammonium salt of perindopril.
Crystalline tert-octylammonium salt of perindopril comprising the following powder x-ray diffraction pattern:
- Angle 2.θ (°)
- Relative intensity (%)
- 5.76
- 61.42
- 7.34
- 17.79
- 9.68
- 50.79
- 13.95
- 18.85
- 14.38
- 23.78
- 14.75
- 100.00
- 15.35
- 43.69
- 16.52
- 73.52
- 17.30
- 17.44
- 19.44
- 41.22
- 19.99
- 34.35
- 20.80
- 57.66
- 22.22
- 33.41
- 22.72
- 54.67
- 23.98
- 34.82
- 26.40
- 45.04
- 26.87
- 19.08.
33 more elements
The Neopentylammonium salt of perindopril.
Dependencies are inferred from the claim text.