Method for treating chronic pain
AssigneeLohocla Research Corporation
InventorBoris Tabakoff
Life of this patent
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Abstract
A method for the treatment of chronic pain in a mammal is provided. The method comprises administering to a mammal (e.g., a human) suffering from chronic pain a pain relieving amount of a diarylureido-dihalokynurenate compound. Preferred diarylureido-dihalokynurenate compounds are esters (e.g., ethyl esters). Particularly preferred are diphenylureido-dichlorokynurenate compounds.
Claims14
A method for the treatment of chronic neuropathic pain in a mammal comprising administering to a mammal suffering from chronic pain a pain relieving amount of a diarylureido-dihalokynurenate compound.
A method for the treatment of chronic neuropathic pain in a mammal comprising administering to a mammal suffering from chronic pain a pain relieving amount of a diarylureido-dihalokynurenate compound having the formula (I),
- a tautomer thereof, or a pharmaceutically acceptable acid addition salt thereof;
- wherein R1 represents hydrogen, an alkyl group of 1 to 12 carbon atoms or a cycloalkyl group of 3 to 8 carbon atoms;
- R2 and R3 each independently represent phenyl or phenyl having one or more alkoxy substituent;
- and
- X1 and X2 each independently represent a halogen substituent.
Dependencies are inferred from the claim text.