Method of detecting platelet thrombosis or organ failure
AssigneeMitsubishi Chemical Medience Corporation
InventorTomoko Ono
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Abstract
A method of detecting platelet thrombosis or organ failure in a patient suffering from disseminated intravascular coagulation (DIC) or systemic inflammatory response syndrome (SIRS), comprising analyzing a von Willebrand factor-cleaving protease and/or a cleaving factor thereof, is disclosed. A kit for detecting platelet thrombosis or organ failure in a patient suffering from DIC or SIRS, comprising an antibody or a fragment thereof which specifically binds to a von Willebrand factor-cleaving protease, and/or an antibody or a fragment thereof which specifically binds to a cleaving factor of the von Willebrand factor-cleaving protease, is disclosed.
Claims10
A method of predicting the amount of a von Willebrand factor-cleaving protease in a patient suffering from disseminated intravascular coagulation or systemic inflammatory response syndrome, said method comprising:
- collecting a sample of blood or plasma from the patient;
- and
- analyzing the blood or plasma sample for a significant increase in the amount of elastase, wherein the significant increase in the amount of said elastase is indicative of a significant decrease in the amount of said von Willebrand factor-cleaving protease.
A method of predicting the amount of elastase in a patient suffering from disseminated intravascular coagulation or systemic inflammatory response syndrome, said method comprising:
- collecting a sample of blood or plasma from the patient;
- and
- analyzing the sample for a significant decrease in the amount of von Willebrand factor-cleaving protease, wherein the significant decrease in the amount of said von Willebrand factor-cleaving protease is indicative of a significant increase in the amount of said elastase.
Dependencies are inferred from the claim text.