Method for studying, determining or evaluating pharmacological actions of a test substance on an sart stressed animal
AssigneeNippon Zoki Pharmaceutical Co., Ltd.
InventorsKusuki Nishioka, Tomohiro Kato, Hiroki Fujisawa
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Abstract
A method for studying, determining or evaluating a pharmacological action of a test substance, the method including subjecting the brain tissue of an SART stressed animal administered with the test substance to an expression proteome analysis, where expression changes of NSF (N-ethylmaleimide sensitive fusion protein), which is or is not modified after translation, in the SART stressed animal administered with the test substance as compared with an SART stressed animal to which a test substance is not administered is used as an index.
Claims10
A method for studying, determining or evaluating a pharmacological action of a test substance, the method comprising:
- subjecting the brain tissue of an SART stressed animal administered with the test substance to an expression proteome analysis,
- wherein expression changes of NSF (N-ethylmaleimide sensitive fusion protein), which is or is not modified after translation, in the SART stressed animal administered with the test substance as compared with an SART stressed animal to which a test substance is not administered is used as an index.
Dependencies are inferred from the claim text.