Back to results
US 7,923,253 B2Granted
Method for identifying type I diabetes mellitus in humans
AssigneeBattelle Memorial Institute
InventorsThomas O Metz, Weijun Qian, Jon M. Jacobs, David G. Camp, II, Richard D. Smith
Life of this patent
Estimating the term…
Abstract
A method and system for classifying subject populations utilizing predictive and diagnostic biomarkers for type I diabetes mellitus. The method including determining the levels of a variety of markers within the serum or plasma of a target organism and correlating this level to general populations as a screen for predisposition or progressive monitoring of disease presence or predisposition.
Claims6
A method of identifying individual humans predisposed for the development of type I diabetes mellitus said method comprising the steps of:
- analyzing a serum or blood plasma sample from a human to determine the quantity of at least three constituents selected from the group consisting of alpha-2-glycoprotein 1 (zinc), corticosteroid-binding globulin, lumican, and clusterin present in said sample;
- and
- comparing said quantity of said at least three constituents to a standardized range of values from healthy individuals to determine whether the level of said at least three constituents is elevated above said standardized range of values wherein a quantity of said at least three constituents that is elevated above said standardized range of values is indicative of type I diabetes mellitus in the human.
Dependencies are inferred from the claim text.