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US 7,923,208 B2Granted
Human cytokine receptor
AssigneeZymoGenetics, Inc.
InventorsScott R. Presnell, Wenfeng Xu, Wayne Kindsvogel, Zhi Chen
Life of this patent
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Abstract
Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.”
Claims3
A method for detecting ovarian cancer, stomach cancer, uterine cancer, rectal cancer, lung cancer and esophageal cancer, comprising:
- incubating a polynucleotide comprising at least 14 contiguous nucleotides of SEQ ID NO:1 or the complement of SEQ ID NO:1 with a tissue or biological sample from a patient under conditions wherein the polynucleotide will hybridize to a complementary polynucleotide sequence;
- detecting hybridization of the polynucleotide in the tissue or biological sample;
- and
- comparing the level of hybridization of the polynucleotide in the tissue or biological sample from the patient to hybridization in a control tissue or biological sample,
- wherein an increase in hybridization in the tissue or biological sample from the patient, relative to the control tissue or biological sample, is indicative of a cancer involving epithelial tissue.
2 more elements
Dependencies are inferred from the claim text.