Compositions for alleviating inflammation and oxidative stress in a mammal

A composition comprising:

• (a) at least about 150 milligrams Bacopa monniera extract, wherein said Bacopa monniera extract having 20 percent bacosides or greater;
• at least about 225 milligrams Silybum marianum (milk thistle) extract, wherein said milk thistle extract is having between about 70 percent and about 80 percent silymarin;
• at least about 150 mg Withania somnifera (ashwagandha) powder;
• at least about 75 milligrams Camellia sinensis (green tea) extract;
• wherein said green tea extract is comprised of 98 percent polyphenols;
• said polyphenols comprised of 45 percent (−)-epigallocatechin gallate;
• at least about 75 milligrams Curcuma longa (turmeric) extract;
• wherein said turmeric extract is comprised of 95 percent curcumin;
• wherein the composition increases the enzyme activity level of at least one antioxidant enzyme selected from the group consisting of:
• superoxide dismutase and catalase and decreases the plasma concentration level of thiobarbituric acid reactive chemical species, when administered in an effective amount to a mammalian subject in need thereof.