Compositions and methods for diagnosing and treating urinary tract infections
AssigneeThe Regents of the University of Michigan
InventorHarry L. T. Mobley
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Abstract
The present invention relates to methods and compositions for treating urinary tract infections. In particular, the present invention relates to vaccines and immune modulators for treating urinary tract infections.
Claims18
A method of inducing an immune response, comprising administering a composition comprising an effective amount of at least a portion of one or more isolated antigens selected from the group consisting of Iha, IreA, IutA and c2482 to a subject under conditions such that said subject generates an immune response to E. coli in said subject's urinary tract.
A method of preventing urinary tract infections by E. coli in a subject, comprising administering a composition comprising an effective amount of at least a portion of one or more isolated antigens selected from the group consisting of Iha, IreA, IutA and c2482 to a subject under conditions such that said subject does not develop symptoms of a urinary tract infection caused by E. coli.
Dependencies are inferred from the claim text.