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US 7,922,761 B2Granted
Artificial vascular prosthesis
AssigneeNicast Ltd.
InventorsAlon Shalev, Alexander Dubson
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Abstract
A vascular prosthesis having a tubular structure is provided. The tubular structure is fabricated from at least two layers wherein at least one layer includes a thrombogenic agent.
Claims26
A vascular prosthesis having a tubular structure, comprising:
- a liner layer;
- a middle layer over the liner layer, including at least two layers wherein at least one layer of said at least two layers includes a thrombogenic agent;
- a cover layer over the middle layer;
- and
- a support structure,
- wherein the support structure is between the liner layer and the middle layer, or between the middle layer and cover layer, or within one of the liner layer and middle layer, and said thrombogenic agent is impregnated within a non-inner layer of said at least two layers.
3 more elements
A method of fabricating a vascular prosthesis, comprising:
- (a) depositing a first material onto a template using a spinning method to thereby form a first layer;
- (b) depositing a second material composed from or including a thrombogenic agent onto said first layer using a spinning method to thereby form the vascular prosthesis;
- and
- (c) removing the vascular prosthesis from said template by ultrasound radiation, wherein the spinning method includes:
- mixing at least one liquefied polymer with at least one conductivity control agents or charge control agents;
- spraying jets of the liquefied polymer from a dispenser;
- forming fibers by evaporating a solvent in the jets of the liquefied polymer;
- collecting the fibers on the surface of the template;
- and
- rotating one of the template and the dispenser and linearly moving the other one of the template and dispenser simultaneously, thereby forming a porous layer on the template.
7 more elements
Dependencies are inferred from the claim text.