Analysing polynucleotide sequences
AssigneeOxford Gene Therapy Limited
InventorEdwin Southern
Life of this patent
Estimating the term…
Abstract
An apparatus is provided for analysing a polynucleotide. The apparatus includes: a support having an impermeable surface; porous material attached to the impermeable surface; and an array of oligonucleotides with predetermined sequences attached to the porous material. The array includes at least two defined cells, the sequence of the oligonucleotides of a first cell being different from the sequence of the oligonucleotides of a second cell, and the oligonucleotides being shorter than the polynucleotide.
Claims22
Apparatus for analysing a polynucleotide, the apparatus comprising:
- a support having an impermeable surface;
- porous material attached to the impermeable surface;
- and an array of oligonucleotides with predetermined sequences attached to the porous material, wherein the array comprises at least two defined cells, the sequence of the oligonucleotides of a first cell is different from the sequence of the oligonucleotides of a second cell, the oligonucleotides are shorter than the polynucleotide, and the oligonucleotides are synthesized in situ.
Apparatus for analysing a polynucleotide, the apparatus comprising:
- a support having an impermeable surface;
- porous material attached to the impermeable surface;
- and an array of oligonucleotides with predetermined sequences attached to the porous material, wherein the array comprises at least two defined cells, the sequence of the oligonucleotides of a first cell is different from the sequence of the oligonucleotides of a second cell, the oligonucleotides are shorter than the polynucleotide, wherein the oligonucleotides are covalently attached to the porous material by a terminal nucleotide.
Dependencies are inferred from the claim text.