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US 7,888,473 B2Granted
Non-functional P2X7 receptor
AssigneeIntreat Pty Limited
InventorsJulian Alexander Barden, Angus Gidley-Baird
Life of this patent
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Abstract
The present invention provides antibodies that specifically bind to P2X7 receptors and distinguish between function and non-functional P2X7 receptors, pharmaceutical compositions and kits containing the antibodies, and methods of using the antibodies for the detection, diagnosis and treatment of disease conditions.
Claims1
An isolated P2X7 receptor having the amino acid sequence as shown in SEQ ID NO:
- 1, wherein the proline at position 210 is in a cis conformation.
Dependencies are inferred from the claim text.