STAT3 phosphorylation inhibitor and notch1 expression inhibitor
AssigneeMeiji Dairies Corporation
InventorsBang Luu, Ellane Mohier, Masashi Yamada, Hiroto Suzuki
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Abstract
The present invention relates to an agent for suppressing STAT3 phosphorylation and for suppressing Notch1 expression comprising as an active ingredient a compound represented by the following formula (1): wherein R1, R2 and R3 each independently represents a hydrogen atom or a methyl group; and X represents a linear or branched alkyl, alkylene or alkenylene group having 10 to 28 carbon atoms.
Claims2
A method for treating cancer comprising administering an effective amount of a composition comprising as an active ingredient a compound which has an activity of improving STAT signal and Notch signal transduction system dysfunction and is represented by the following formula (I):
- wherein R1, R2 and R3 each independently represents a hydrogen atom or a methyl group;
- and
- X represents a linear or branched alkyl group,
- in a mammal in need of such treatment.
A method for treating cancer comprising administering an effective amount of a composition comprising as an active ingredient a compound which has an activity of suppressing STAT3 phosphorylation and suppressing Notch1 expression and is represented by the following formula (1):
- wherein R1, R2 and R3 each independently represents a hydrogen atom or a methyl group;
- and
- X represents a linear or branched alkyl group,
- in a mammal in need of such treatment.
Dependencies are inferred from the claim text.