US 7,888,392 B2 · Ointment

Abstract

An ointment containing a compound represented by formula (I): [wherein R1 represents any group of a group represented by the formula: —(CH2)4—S—CH2—CO2H, a group represented by the formula: —(CH2)4—S—CH2—CO2CH3, a group represented by the formula: —(CH2)4—C≡C—CO2H, a group represented by the formula: —CH2—S—(CH2)2—S—CH2—CO2H, and a group represented by the formula: —CH2—S—(CH2)4—CO2H], and an oleaginous base, is an ointment containing a compound which is effective for atopic symptoms, and is an ointment having low skin irritancy and excellent storage stability, thus, can be used as a pharmaceutical product effective for the pruritus caused by atopy or the like.

Claims4

Dependent claims

An oleaginous ointment consisting essentially of a compound represented by formula (II):

and an oleaginous base,
wherein the compound represented by formula (II) is dispersed in the oleaginous base in a solid state or in an oily state, such that the compound is not dissolved in the oleaginous base;
and
wherein the compound represented by formula (II) is present in the ointment in the range of about 0.000001% to 0.1% by weight;
wherein the oleaginous base comprises a white petrolatum purified by removing impurities;
and,
wherein the ointment is produced by adding a dispersion obtained by dispersing the compound represented by formula (II) in the oleaginous base, to the oleaginous base maintained at a temperature of 45° C. or higher and 55° C. or lower, and mixing the dispersion and the oleaginous base with stirring.

4 more elements

Dependencies are inferred from the claim text.

Ointment

Life of this patent

Ointment

Life of this patent

Abstract

Claims4