Organic compounds

A compound of Formula (I):

• wherein
• the asterisk * designates a chiral centre of (R) or (S) configuration;
• V is absent or is ethylene;
• W is —C(O)— or —S(O)l—;
• X is a linker having 1 to 12 in-chain atoms and comprising one or more linkages selected from —O—, —C(O)—, —S(O)l—, —N(R9)— and hydrocarbylene optionally substituted with 1, 2, 3, 4 or 5 R11;
• Y is a linker selected from —O—, —N(R9)—, —C(O)—, —C(O)O—, —C(O)N(R9)—, —S(O)l— and S(O)lN(R9)—;
• R1 is selected from hydrogen;
• —N(R9)(R10) hydrocarbyl optionally substituted with 1, 2, 3, 4 or 5 R11;
• hydrocarbyloxy optionally substituted with 1, 2, 3, 4 or 5 R11;
• and
• —(CH2)k-heterocyclyl optionally substituted with 1, 2, 3, 4 or 5 R11;
• or, when Y is —N(R9)—, R1 and R9 taken together with the nitrogen atom to which they are attached may form a heterocycle, wherein said heterocycle is bound to X via said nitrogen atom and is optionally substituted with 1, 2, 3, 4 or 5 R11;
• R2 and R3 are each independently selected from R8, —OR8;
• —C(O)R8;
• —C(O)OR8 and —S(O)lR9;
• R4 and R5 are each independently selected from hydrogen, hydroxy, halogen and C1-6 alkyl optionally substituted with 1, 2, 3, 4 or 5 R11;
• R6 is aryl or heteroaryl, either of which is optionally-substituted with 1, 2, 3, 4 or 5 R11;
• R8 is selected from hydrogen;
• hydrocarbyl optionally substituted with 1, 2, 3, 4 or 5 R11;
• and —(CH2)k-heterocyclyl optionally substituted with 1, 2, 3, 4 or 5 R11;
• R9 and R10 are each independently selected from R8, —OR8, —C(O)R8, —C(O)OR8 and —S(O)lR8;
• or R9 and R10 taken together with a nitrogen atom to which they are attached form heterocyclyl optionally substituted with 1, 2, 3, 4 or 5 R11;
• each R11 is independently selected from R12;
• hydrocarbyl optionally substituted with 1, 2, 3, 4 or 5 R12;
• and —(CH2)k-heterocyclyl optionally substituted with 1, 2, 3, 4 or 5 R12;
• R12 is independently selected from halogen, trifluoromethyl, cyano, nitro, oxo, ═NR13, —OR13, —C(O)R13, —C(O)N(R13)R14, C(O)OR13, —OC(O)R13, —S(O)lR13, —S(O)lN(R13)R14, —N(R13)R14, —N(R13)N(R13)R14, —N(R13)C(O)R14 and —N(R13)S(O)lR13;
• R13 and R14 are each independently hydrogen or selected from hydrocarbyl and —(CH2)k-heterocyclyl, either of which is optionally substituted with 1, 2, 3, 4 or 5 substituents independently selected from oxo, halogen, cyano, amino, hydroxy, C1-6 alkyl and C1-6 alkoxy;
• k is 0, 1, 2, 3, 4, 5 or 6;
• and
• l is 0, 1 or 2;
• or a pharmaceutically acceptable salt or prodrug thereof.