Benzaepinones as sodium channel blockers
AssigneeMerck Sharp & Dohme Corp.
InventorsScott B. Hoyt, Clare London, Dong Ok, William H. Parsons
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AssigneeMerck Sharp & Dohme Corp.
InventorsScott B. Hoyt, Clare London, Dong Ok, William H. Parsons
Estimating the term…
Benzazepinone compounds represented by Formula (I), or pharmaceutically acceptable salts thereof. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier. Methods of treating conditions associated with, or caused by, sodium channel activity, including, for example, acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain, epilepsy, irritable bowel syndrome, urinary incontinence, pruritis, itchiness, allergic dermatitis, depression, anxiety, multiple sclerosis, and bipolar disorder, comprise administering an effective amount of the present compounds, either alone, or in combination with one or more other therapeutically active compounds. A method of administering local anesthesia comprises administering an effective amount of a compound of the instant invention, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier.
A compound represented by Formula (I):
Dependencies are inferred from the claim text.