Back to results
US 7,888,119 B2Granted
Tissue substitutes comprising stem cells and reduced ceria
AssigneeUniversity of Central Florida Research Foundation, Inc.
InventorsKiminobu Sugaya, Stephanie Merchant, Sudipta Seal, Petya Georgieva, Manny Vrotsos
Life of this patent
Estimating the term…
Abstract
A biocompatible composite includes a solid biocompatible material and a plurality of living human progenitor or living stem cells attached thereto. The biocomposite provides a stable interface with endogenous tissue and the implanted composition resulting in accelerated repair to damaged bones and tissues.
Claims14
A biocomposite, comprising:
- a biocompatible solid material, and
- a plurality of living human progenitor or living stem cells attached to a surface of said biocompatible material;
- wherein the biocompatible material comprises cerium nanoparticles on surfaces of said biocompatible material;
- wherein the cerium nanoparticles comprise ceria nanoparticles having Ce4+ molecules and reduced ceria nanoparticles having Ce3+ molecules, the cerium nanoparticles having an average particle size of less than 20 nm;
- and
- wherein the average particle size of less than 20 nm is effective to provide an increased amount of the reduced ceria nanoparticles on the surfaces of said biocompatible material relative to larger cerium nanoparticles.
3 more elements
Dependencies are inferred from the claim text.