Cloning of honey bee allergen C
AssigneePLS-Design GmbH
InventorsSimon Blank, Benjamin Bockisch, Thomas Grunwald
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Abstract
The present invention relates to a nucleic acid encoding a polypeptide capable of binding to IgE from subjects allergic to venom of an insect from the order Hymenoptera having a homology of more than 70% to the amino acid sequence of SEQ ID NO: 2, which is the honey bee allergen C (Api m 5). The invention further relates to expression vectors, host cells and polypeptides encoded by the nucleic acid, as well as diagnostic and pharmaceutical uses thereof.
Claims16
A nucleic acid encoding a polypeptide capable of binding to IgE from subjects allergic to venom of an insect from the order Hymenoptera, wherein said polypeptide has the amino acid sequence of SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.