Highly purified and stabilized Na,K-ATPase isoforms and methods of producing same
AssigneeYeda Research and Development Co. Ltd.
InventorsSteven J. D. Karlish, Haim Garty, Yael Lifshitz, Rivka Goldschleger
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Abstract
A composition of matter comprising active Na,K-ATPase is disclosed, each Na,K-ATPase comprising an α and β subunit, the Na,K-ATPase being at least 85% purified. Methods of purifying same and uses thereof are also disclosed.
Claims18
A composition of matter comprising catalytically active Na,K-ATPase, said Na,K-ATPase comprising an α and β subunit, said Na,K-ATPase being at least 85% purified, wherein said Na,K-ATPase comprises a human α1 subunit and a porcine β1 subunit.
A composition of matter comprising catalytically active Na,K-ATPase, said Na,K-ATPase comprising an α and βsubunit, said Na,K-ATPase being at least 85% purified, wherein said Na,K-ATPase comprises a human α2 subunit and a porcine β1 subunit.
A composition of matter comprising catalytically active Na,K-ATPase, said Na,K-ATPase comprising an α and β subunit, said Na,K-ATPase being at least 85% purified, wherein said Na,K-ATPase comprises a porcine α1 subunit and a porcine β1 subunit.
Dependencies are inferred from the claim text.