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US 7,887,860 B2Granted
Anti-bacterial plant compositions
AssigneeInter American University of Puerto Rico
InventorAnne D. Frame
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AssigneeInter American University of Puerto Rico
InventorAnne D. Frame
Estimating the term…
The invention provides a pharmaceutical composition which comprises a pharmaceutical carrier and at least one compound selected from the group consisting of cobaltocene-octamethyl, stigmastan-3,5 -diene,galaxolide, benzyl salicylate, eucalyptol, and α-pinene. Also provided is a method of preparing a composition having antimicrobial activity comprising extracting a plant material in an organic solvent, contacting the extracted material to a chromatographic column, and eluting from the chromatographic column with a mobile polar phase to obtain a composition. The plant material is from Mammea Americana, Marchantaceae polymorpha, or Callistemon citrinus. Also provided is a method of inhibiting the growth of a mycobacterium, comprising administering a composition comprising a carrier and at least one compound selected from among cobaltocene-octamethyl, stigmastan, 3,5-diene, friedelin, galaxolide, benzyl salicylate, eucalyptol, and α-pinene.
A method of preparing a composition having antibacterial activity comprising extracting Mammea Americana leaves in an organic solvent, contacting the extract with a chromatographic separation system, eluting a fraction comprising cobaltocene octomethyl from the chromatographic separation system with a mobile polar phase and collecting said fraction.
A method of preparing a composition having antibacterial activity comprising extracting Merchantia polymorpha leaves in an organic solvent, contacting the extract with a chromatographic separation system, eluting a fraction comprising cobaltocene octomethyl from the chromatographic separation system with a mobile polar phase and collecting said fraction.
A method for inhibiting the growth of Mycobacterium comprising administering to a patient in need thereof, a pharmaceutical composition comprising an effective amount of cobaltocene octomethyl.
A method for inhibiting the growth of Mycobacterium in-vitro, said method comprising administering a composition comprising an effective amount of cobaltocene octomethyl to inhibit in-vitro growth of Mycobacterium.
Dependencies are inferred from the claim text.