Methods of administering a dermatological agent to a subject
AssigneesTeikoku Pharma USA, Inc., Teikoku Seiyaku Co., Ltd.
InventorsJohn Koo, Jutaro Shudo, Sadanobu Shirai
Life of this patent
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Abstract
Methods for administering a dermatological agent to a subject are provided. In the subject methods an effective amount of a topical formulation of the dermatological agent is topically applied to a host. The topically applied formulation of dermatological agent is then occluded with a hydrogel patch, where a feature of the hydrogel patch is that it lacks a pharmaceutically active agent. Also provided are methods of treating a subject for a disease condition by administering a dermatological agent to the subject. Also provided are kits for use in practicing the subject methods. The subject methods and compositions find use in a variety of different applications.
Claims28
A method of treating a host for a skin disease condition, said method comprising:
- (a) topically applying an effective amount of a topical formulation of a dermatological agent to said host;
- and
- (b) occluding said topically applied topical formulation of said dermatological agent with a blank hydrogel patch composition to administer said dermatological agent to said host, wherein said blank hydrogel patch composition comprises:
- (i) a water-soluble polymer gel;
- (ii) water;
- (iii) a water retaining agent;
- and
- (iv) a cross-linking agent;
- and
- wherein said blank hydrogel patch composition is present on a support that is impermeable to said blank hydrogel patch composition;
- to treat said host for said skin disease condition.
A method of treating a host for a skin disease condition by administering to said host a dermatological agent, said method comprising:
- (a) topically applying an effective amount of a topical formulation of said dermatological agent to said host;
- (b) occluding said topically applied topical formulation of said dermatological agent with a blank hydrogel patch composition to produce an occluded topically applied formulation, wherein said blank hydrogel patch composition comprises:
- (i) a water-soluble polymer gel;
- (ii) water;
- (iii) a water retaining agent;
- and
- (iv) a cross-linking agent;
- and
- wherein said blank hydrogel patch composition is present on a support that is impermeable to said blank hydrogel patch composition;
- and
- maintaining said occluded topically applied formulation for a period of time sufficient to treat said host for said skin disease condition.
Dependencies are inferred from the claim text.