Oat extracts: refining, compositions and methods of use
AssigneeCeapro Inc.
InventorsMark J. Redmond, David A. Fielder
Life of this patent
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Abstract
A simple and efficient method for the production of stable, clear, high-potency oat extracts is disclosed. The method employs the use of differential dissociation constants and ultrafiltration to stabilize extracts, prevent hazing, and prevent the loss of functional activity as an anti-irritant and anti-oxidant. Also disclosed are compositions of oat extracts derived from whole oat grains and oatmeal. Further disclosed are compositions of oat extracts for use in cosmetic, nutraceutical, therapeutic medical and veterinary preparations.
Claims31
A stable composition for cosmetic, food or pharmaceutical use containing 1 to 1500 ppm avenanthramide prepared by a method comprising the following steps:
- a. milling whole oats;
- b. extracting the resulting oatmeal with a solvent comprising water and a primary or secondary alcohol;
- c. clarifying the extract by adjusting the pH of the resulting oat extract to <4.0;
- d. membrane filtration of the oat extract with a pH <4.0 through a membrane <104 MWCO, wherein the composition contains less than 0.01 wt-% proteins with a molecular weight greater than 10,000 Da.
A stable composition for cosmetic, food or pharmaceutical use containing between 3 and 450 ppm avenanthramide, prepared by a method comprising the following steps:
- a. milling whole oats;
- b. extracting the resulting oatmeal with a solvent comprising water and a primary or secondary alcohol;
- c. clarifying the extract by adjusting the pH of the resulting oat extract to <4.0;
- d. membrane filtration of the oat extract with a pH <4.0through a membrane <104 MWCO, wherein the composition contains less than 0.01wt-% proteins with a molecular weight greater than 10,000 Da.
A stable oat extract containing at least 1 ppm avenanthramide prepared by a method comprising the following steps:
- a. milling whole oats;
- b. extracting the resulting oatmeal with a solvent comprising water and a primary or secondary alcohol;
- c. clarifying the extract by adjusting the pH of the resulting oat extract to <4.0;
- d. membrane filtration of the oat extract with a pH <4.0 through a membrane <104 MWCO, wherein the stable oat extract contains less than 0.01 wt-% proteins with a molecular weight greater than 10,000Da.
A stable oat extract containing between 3 and 450 ppm avenanthramide prepared by a method comprising the following steps:
- a. milling whole oats;
- b. extracting the resulting oatmeal with a solvent;
- c. clarifying the extract by adjusting the pH of the resulting oat extract to <4.0;
- d. membrane filtration of the clarified oat extract through a membrane <104 MWCO, wherein the stable oat extract contains less than 0.01 wt-% proteins with a molecular weight greater than 10,000 Da.
Dependencies are inferred from the claim text.