Interferon antagonists useful for the treatment of interferon related diseases
AssigneeMeiogen Biotechnology Corporation
InventorLeonard E. Maroun
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Abstract
The present invention relates to a process for ameliorating or preventing diseases that are caused, in part, by an increased level of, and/or an abnormal responsivity to, interferon. Specifically, the invention provides compositions and methods for preventing and treating subjects suffering from, or at risk for, such diseases. Such methods include the administration of a pharmacological preparation of interferon binding proteins that antagonize interferon's action. This invention comprises compositions of interferon binding proteins that can inhibit the activity of Type I and II.
Claims17
A method of reducing the incidence of pathological effects of a disease or decreasing the pathological effects of a disease, wherein said pathological effects are associated with excessive levels of one or more interferons in a patient suffering from said disease, comprising administering a therapeutically effective amount of one or more interferon binding proteins to said patient, wherein said one or more interferon binding proteins is selected from the group consisting of B18R, B8R, and a combination thereof.
A method of reducing the incidence of pathological effects of transplant rejection or decreasing the pathological effects of transplant rejection, wherein said pathological effects are associated with excessive levels of one or more interferons in a patient receiving said transplant, comprising administering a therapeutically effective amount of one or more interferon binding proteins to said patient, wherein the one or more interferon binding proteins is selected from the group consisting of B18R, B8R, and a combination thereof.
Dependencies are inferred from the claim text.