Mammalian receptor proteins DCRS5; method of treatment
AssigneeSchering Corporation
InventorsMadaline Chirica, Robert A. Kastelein, Kevin Moore, Christi L. Parham
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Abstract
Nucleic acids encoding mammalian, e.g., primate, receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described.
Claims14
A method of treating a human subject experiencing rheumatoid arthritis comprising administering an effective amount of an antagonist antibody that specifically binds to DCRS5 (SEQ ID NO:
- 2), or an antigen binding fragment thereof.
A method of treating a human subject experiencing rheumatoid arthritis comprising administering an effective amount of an antagonist antibody that specifically binds to a polypeptide comprising residues 1-606 of SEQ ID NO:
- 2, or an antigen binding fragment thereof.
Dependencies are inferred from the claim text.