Methods of treating cancer by administering antibodies to CD200
AssigneeTrillium Therapeutics Inc.
InventorsReginald M. Gorczynski, David A. Clark
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Abstract
Methods and compositions for regulating immunity are disclosed. For enhancing an immune response, agents that inhibit OX-2 are administered. Such methods are useful in treating cancer. For suppressing an immune response, an OX-2 protein or a nucleic acid encoding an OX-2 protein is administered. Such methods are useful in preventing graft rejection, fetal loss, autoimmune disease, allergies and in inducing tumor cell growth.
Claims12
A method of inhibiting or reducing leukemia cell growth comprising administering an effective amount of an antibody that binds to and inhibits a CD200 protein to a cell or an animal in need thereof.
A method of inhibiting or reducing leukemia cell growth comprising:
- determining whether CD200 is upregulated in a subject;
- and administering to the subject an antibody that binds to and inhibits CD200.
A method of treating a leukemia comprising:
- determining whether CD200 is upregulated in a subject afflicted with leukemia;
- and administering to the subject an antibody that binds to and inhibits CD200.
Dependencies are inferred from the claim text.