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US 7,877,146 B2Granted
Methods of treating medical conditions by neuromodulation of the sympathetic nervous system
AssigneeThe Cleveland Clinic Foundation
InventorsAli Rezai, Mehdi Ansarinia
Life of this patent
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Abstract
The present invention is directed to systems and methods for treating respiratory or pulmonary medical conditions by neuromodulation of a target site of the sympathetic nervous system and preferably a target site in communication with a sympathetic nerve chain. A system for treating a respiratory or pulmonary medical condition incorporating a closed-loop feedback system is also provided.
Claims5
A method of alleviating a bronchial disorder in a patient suffering therefrom comprising:
- placing an electrode in electrical contact with a target site of the patient, the target site comprising a cervical ganglion or an upper thoracic sympathetic ganglion of the sympathetic nervous system;
- detecting the patient's respiratory function via a sensor and generating a sensor signal;
- and
- activating the electrode to initiate application of an electrical signal to the target site in response to the sensor signal or adjusting application of an electrical signal to the target site in response to the sensor signal to alleviate the patient's bronchial disorder, wherein the electrical signal has a voltage range of 0.1 μV to about 20 V and a frequency range of about 2 Hz to about 2500 Hz,
- wherein the bronchial disorder is asthma.
2 more elements
Dependencies are inferred from the claim text.