Back to results
US 7,875,296 B2Granted
Conformable tissue repair implant capable of injection delivery
AssigneeDePuy Mitek, LLC
InventorsFrancois Binette, Joseph J. Hammer, Krish Mukhopadhyay, Joel Rosenblatt
Life of this patent
Estimating the term…
Abstract
A conformable tissue implant is provided for use in repairing or augmenting a tissue defect or injury site. The tissue implant contains a tissue carrier matrix comprising a plurality of biocompatible, bioresorbable granules and at least one tissue fragment in association with the granules. The tissue fragment contains one or more viable cells that can migrate from the tissue and populate the tissue carrier matrix. Also provided is a method for injectably delivering the tissue implant.
Claims22
A tissue repair implant comprising:
- a tissue carrier matrix in the form of an injectable suspension, the tissue carrier matrix comprising a plurality of biocompatible, bioresorbable granules and at least one tissue fragment in association with the tissue carrier matrix, the at least one tissue fragment having an effective amount of viable cells that can migrate out of the tissue fragment and populate the tissue carrier matrix, the granules having an average outer diameter in a range of about 150 to about 600 μm, the granules comprising at least one of aliphatic polyesters, copoly(ether-esters), solid copolymers of fatty acid esters of glycerol and succinic acid, polyoxaesters, collagen, gelatin, albumin, hyaluronate, glycosaminoglycans, polyanhydrides, polysaccharides, polyphosphazines, subintestinal mucosa, and acellular tissues.
A tissue repair implant comprising:
- a tissue carrier matrix in the form of an injectable suspension, the tissue carrier matrix comprising a plurality of biocompatible, bioresorbable granules and at least one tissue fragment in association with the tissue carrier matrix, the at least one tissue fragment having an effective amount of viable cells that can migrate out of the tissue fragment and populate the tissue carrier matrix, the at least one tissue fragment having a particle size in the range of about 0.1 to about 2 mm3, and wherein the biocompatible, bioresorbable granules have an average outer diameter in a range of about 150 to about 600 μm.
Dependencies are inferred from the claim text.