Treatment of Parkinson's disease and related disorders using postpartum derived cells
AssigneeEthicon, Inc.
InventorsDarin J. Messina, Sanjay Mistry, L. S. Klaudyne Hong, Brian C. Kramer, Michael J. Romanko
Life of this patent
Estimating the term…
Abstract
Cells derived from postpartum tissue such as the umbilical cord and placenta, pharmaceutical compositions comprising such cells, and methods for using such cells and pharmaceutical compositions to treat patients having a neurodegenerative condition of the substantia nigra or striatum, such as Parkinson's disease, are provided.
Claims17
A method of treating a patient having Parkinson's Disease or parkinsonism, the method comprising administering to striatum of the patient cells in an amount effective to treat Parkinson's Disease or parkinsonism, wherein the cells are isolated from mammalian umbilical cord tissue substantially free of blood or are expanded in culture from a cell isolated from mammalian umbilical cord tissue substantially free of blood, wherein the cells are capable of self-renewal and expansion in culture, and require L-valine for growth;
- and wherein the cells do not produce CD117.
Dependencies are inferred from the claim text.