Fused bicycloheterocycle substituted azabicyclic alkane derivatives

The compound of formula (I),

• or a pharmaceutically acceptable salt, ester, amide, or prodrug thereof, wherein
• n is 1, 2 or 3;
• A is N or N+—O−;
• R is hydrogen, alkyl, cycloalkylalkyl and arylalkyl;
• L is selected from the group consisting of O, S, and —N(Ra)—;
• Ar1 is a pyridinylene group substituted with 0, 1, 2 or 3 substituents selected from the group consisting of acyl, acyloxy, alkenyl, alkoxy, alkoxyalkoxy, alkoxyalkyl, alkoxycarbonyl, alkoxyimino, alkoxysulfonyl, alkyl, alkylsulfonyl, alkynyl, amino, carboxy, cyano, formyl, haloalkoxy, haloalkyl, halo, hydroxy, hydroxyalkyl, mercapto, nitro, thioalkoxy,—NRgRj, (NRgRj)alkyl, (NRgRj)alkoxy, (NRgRj)carbonyl, and (NRgRj)sulfonyl, wherein Rg and Rj are each independently selected from the group consisting of hydrogen and alkyl;
• and
• Ar2 is a bicyclic heteroaryl substituted with 0, 1, 2, or 3 substituents selected from the group consisting of alkenyl, alkoxy, alkoxyalkoxy, alkoxyalkyl, alkoxycarbonyl, alkoxysulfonyl, alkyl, alkylcarbonyl, alkylcarbonyloxy, alkylsulfonyl, alkylthio, alkynyl, carboxy, cyano, formyl, haloalkoxy, haloalkyl, halo, hydroxy, hydroxyalkyl, mercapto, nitro, —NRgRj, (NRgRj)alkyl, (NRgRj)alkoxy, (NRgRj)carbonyl, and (NRgRj)sulfonyl, wherein Rg and Rj are each independently selected from the group consisting of hydrogen and alkyl;
• and
• Ra is selected from the group consisting of hydrogen, alkyl and alkylcarbonyl.