Compounds as cannabinoid receptor ligands

A compound of formula (I),

• or a pharmaceutically suitable salt or prodrug thereof, wherein
• - - - is absent or is a bond;
• m, n are each independently 0, 1 or 2;
• p is 1 or 2;
• q and r are each independently 0 or 1;
• s is 0, 1, 2, 3, or 4;
• R1 is selected from the group consisting of alkyl, alkoxyalkyl, alkylcarbonyl, cyano, cyanoalkyl, halo, haloalkyl, R4O2C—, RcRdNC(O)—, and RcRdNS(O)2—;
• R2 is selected from the group consisting of aryl, cycloalkyl, heteroaryl, heterocycle, —O(Rh), and ReRfN—;
• R3 is selected from the group consisting of alkyl, alkoxyalkyl, haloalkyl, hydroxyalkyl, R5-C(O)—, R5-C(═N—ORp)-, R6OC(O)—, RgRjNC(O)—, R5-S(O)2-, and RgRjNS(O)2-;
• R4 is selected from the group consisting of alkyl, arylalkyl, haloalkyl, heteroarylalkyl, and heterocyclealkyl;
• R5, at each occurrence, is selected from the group consisting of alkyl, alkoxyalkyl, aryl, cycloalkyl, haloalkyl, heteroaryl, and heterocycle;
• R6 is selected from the group consisting of alkyl, arylalkyl, haloalkyl, cycloalkyl, cycloalkylalkyl, heterocyclealkyl, and heteroarylalkyl;
• Rc and Rd, at each occurrence, are each independently selected from the group consisting of hydrogen and alkyl, or Rc and Rd together with the nitrogen atom to which they are attached form a heterocyclic ring;
• Re is selected from the group consisting of hydrogen, alkyl, cycloalkyl, and alkylcarbonyl;
• Rf is selected from the group consisting of hydrogen and alkyl;
• Rg, at each occurrence, is independently selected from the group consisting of hydrogen, alkyl, arylalkyl, cycloalkyl, cycloalkylalkyl, haloalkyl, hydroxyalkyl, alkoxyalkyl, haloalkoxyalkyl, heteroarylalkyl, heterocyclealkyl, and heterocyclealkyl;
• Rj, at each occurrence, is independently selected from the group consisting of hydrogen, alkyl, and haloalkyl;
• Rh is a cycloalkyl ring optionally substituted with 1, 2, 3, 4, 5, or 6 substituents independently selected from the group consisting of alkyl, alkenyl, alkynyl, halogen, hydroxy, alkoxy, haloalkyl, arylalkyl, heteroarylalkyl, cycloalkyl, and heterocyclealkyl;
• and
• Rp is selected from the group consisting of hydrogen and alkyl.