US 7,855,557 B2Granted

Gas nuclear magnetic resonance apparatus

AssigneeNational University Corporation Kobe University

InventorKiyokazu Fuke

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Abstract

An NMR apparatus is provided, which is capable of being used for mass spectrometry and structure determination of a gas sample. The NMR apparatus includes: a sample vaporization unit 1 having a sample vaporization chamber 1a; an ionization unit 2 having a ionization chamber 2a and connected to one end of the sample vaporization unit 1 so that the ionization chamber 2a communicates with the sample vaporization chamber 1a; a long-length pipe 3 connected to one end of the ionization unit 2 so that the inside of the pipe 3 communicates with the ionization chamber 2a; a cooling unit 4 having a cooling chamber 4a and connected to one end of the long-length pipe 3 so that the cooling chamber 4a communicates with the inside of the long-length pipe 3; a superconducting magnet 5 having a tubular portion 5a into which the long-length pipe 3 is inserted, the superconducting magnet 5 being capable of applying a magnetic field and a gradient magnetic field in the axial direction of the long-length pipe 3; an ion guide 6 which decelerates gas ions; a mass analysis unit 7 which is used for mass screening of gas ions; and a nuclear magnetic force amplification unit 8 which amplifies the nuclear magnetic force of gas ions.

Claims7

Dependent claims

A gas nuclear magnetic resonance apparatus comprising:

a mass analysis unit including:
an ICR cell disposed in a high vacuum space to which a predetermined magnetic field is applied in a predetermined direction, the ICR cell conducting mass screening of introduced gas ions;
and a first gas ion controller which introduces the gas ions into the ICR cell, keeps the gas ions in the ICR cell, or discharges the gas ions from the ICR cell;
and
a nuclear magnetic force amplification unit located within said gas nuclear magnetic resonance apparatus including:
a nuclear magnetic force amplification cell disposed in a high vacuum space to which a predetermined gradient magnetic field is applied in the predetermined direction, into which cell gas ions subjected to mass screening in the mass analysis unit are introduced;
an amplification unit which amplifies, in the nuclear magnetic force amplification cell, nuclear magnetic forces only of gas ions having a predetermined nuclear magnetic resonance frequency;
and a second gas ion controller which introduces the gas ions into the nuclear magnetic force amplification cell, keeps the gas ions in the nuclear magnetic force amplification cell, or discharges the gas ions from the nuclear magnetic force amplification cell,
wherein the gas ions having the predetermined nuclear magnetic resonance frequency, which have been amplified in the nuclear magnetic force amplification unit, are reintroduced into the ICR cell.

6 more elements

A gas nuclear magnetic resonance apparatus comprising:

an ionization unit which ionizes a sample gas to generate gas ions;
a mass analysis unit including:
an ICR cell which has a tubular shape and conducts mass screening of the gas ions introduced from the ionization unit to the inside of the ICR cell;
and a first pair of electrodes which are provided so as to sandwich the ICR cell in an axial direction and introduce the gas ions into the ICR cell, keep the gas ions in the ICR cell, or discharge the gas ions from the ICR cell, the mass analysis unit being provided in a high vacuum space to which a predetermined magnetic field is applied in the axial direction;
and
a nuclear magnetic force amplification unit located within said gas nuclear magnetic resonance apparatus including:
a tubular cell provided in a portion to which a predetermined gradient magnetic field is applied in the axial direction within the high vacuum space to which the predetermined magnetic field is applied, into which tubular cell gas ions subjected to mass screening in the mass analysis unit are introduced;
two pairs of RF coils provided so as to sandwich the tubular cell in the axial direction, the two pairs of RF coils being capable of applying an RF magnetic field perpendicularly to the axial direction of the tubular cell at both axial ends of the tubular cell;
and a second pair of electrodes provided so as to sandwich, in the axial direction, a space to which the RF magnetic field is applied, the second pair of electrodes introducing the gas ions from the mass analysis unit to the tubular cell, keeping the gas ions in the tubular cell, or discharging the gas ions from the tubular cell, the nuclear magnetic force amplification unit amplifying nuclear magnetic forces of the gas ions,
wherein, among the gas ions, only the gas ions corresponding to a predetermined nuclear magnetic resonance frequency are arranged to have nuclear magnetic forces amplified by the pairs of RF coils in the nuclear magnetic force amplification unit, and are reintroduced to the ICR cell, so that ion concentration and velocity increment are measured.

7 more elements

Dependencies are inferred from the claim text.

Facts

Application: 12/161,068Filed 9 Jan 2007
Priority: JP 2006-00688716 Jan 2006
Published: US 2010/0156410 A124 Jun 2010
Granted: 21 Dec 2010
Term ends: Not estimatedThe source records don’t support an estimate.

Classification9 codes

G01R 33/46
Using nuclear magnetic resonance [NMR]: nMR spectroscopy
G01N 24/002
Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects: using…
G01N 24/087
By using nuclear magnetic resonance: structure determination of a chemical compound, e.g. of a biomolecule such as a protein
G01N 24/14
Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects: by using…