Mouse spermatogenesis genes related to human male sterility
AssigneeJapan Science and Technology Agency
InventorsYoshitake Nishimune, Hiromitsu Tanaka, Masami Nozaki
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Abstract
The present invention provides a polynucleotide or a complementary sequence thereof, which polynucleotide is complementary to mRNA transcribed from a human male infertility-associated gene Scot-t, and has one or more mutations selected from the following group: “t” at 870th position is replaced by “g”; and “t” at 1667th position is replaced by “c”, in the DNA sequence of SEQ ID NO:168; various molecular biological materials relating thereto; various molecular biological materials relating to male infertility-associated gene mutations; and various test methods and diagnostic methods using the same.
Claims1
A isolated polynucleotide which is the cDNA of human male infertility-associated gene Scot-t and consists of the nucleotide sequence of SEQ ID NO:
- 168, and has the following mutation:
- “t” at 870th position is replaced by “g”.
Dependencies are inferred from the claim text.