Cosmetic and pharmaceutical compounds for inducing the synthesis of SIRT proteins in skin and methods of use thereof
AssigneeISP Investments Inc.
InventorsClaude Dal Farra, Nouha Domloge, Jean-Marie Botto
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Abstract
A cosmetic dermo-pharmaceutical, or dermatological composition having as an active agent in an acceptable cosmetic or pharmaceutical medium, at least one compound able to activate the synthesis or SIRT proteins in skin cells.
Claims13
A method for non-therapeutic care intended to improve appearances and general cutaneous performance of skin, comprising:
- administering to the skin an effective amount of at least one compound able to activate endogenous synthesis of sirtuin (SIRT1) protein, wherein the compound is a peptide of sequence
- (I):
- (AA)n-Gly-Leu-Tyr-Asp-Asn-Leu-Glu-(AA)n
- (AA) is any particular amino acid, and n is a whole number and ranges from 0 to 3.
A method to protect skin, against negative effects of UVB radiation, comprising:
- administering to the skin an effective amount of at least one compound able to activate endogenous synthesis of sirtuin (SIRT1) protein, wherein the compound is a peptide of sequence
- (I):
- (AA)n-Gly-Leu-Tyr-Asp-Asn-Leu-Glu-(AA)n,
- (AA) is any particular amino acid, and n is a whole number and ranges from 0 to 3.
A cosmetic or pharmaceutical composition wherein, in a cosmetically or pharmaceutically acceptable medium, at least one compound is able to activate the synthesis of sirtuin (SIRT1) protein in skin cells, wherein the compound is a peptide of sequence (I):
- (AA)n-Gly-Leu-Tyr-Asp-Asn-Leu-Glu-(AA)n, (AA) is any particular amino acid, and n is a whole number and ranges from 0 to 3.
Dependencies are inferred from the claim text.