Hyarulonic acid derivative based three dimensional matrix
AssigneeFidia Advanced Biopolymers S.r.l.
InventorsAnthony P. Hollander, Alessandria Pavesio
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Abstract
Use of a biological material containing: e) a three-dimensional matrix based on a hyaluronic acid derivative and optionally f) chondrocytes and/or mesenchymal cells partially or completely differentiated towards chondrocytes for the preparation of a graft to be surgically implanted into a joint cartilage damaged by or to be protected against a degenerative and/or inflammatory pathology.
Claims9
A surgical method for recovering or protecting a joint cartilage from a degenerative and/or inflammatory pathology, associated with the production of IL-1, selected from osteoarthritis, psoriatic and rheumatoid arthritis, said method comprising the step of implanting into a subject in need thereof a graft consisting essentially of a biological material containing:
- a) a three-dimensional matrix based on a hyaluronic acid derivative in the form of a non-woven tissue and selected from the class of hyaluronic acid benzyl esters having a percentage of esterification ranging from 75 to 100%;
- and optionally
- b) chondrocytes and/or mesenchymal cells partially or completely differentiated towards chondrocytes.
Dependencies are inferred from the claim text.