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US 7,842,282 B2Granted
Generation of therapeutic microfoam
AssigneeBTG International Limited
InventorsAnthony David Harman, Paul Harper, Neil Pollock, Gary Stewart Sinclair
Life of this patent
Estimating the term…
Abstract
A method for producing a microfoam suitable for use in scleropathy of blood vessels comprises introducing a physiologically acceptable blood-dispersible gas into a container (1) holding an aqueous sclerosant liquid and releasing the mixture of blood-dispersible gas and sclerosant liquid, whereby upon release of the mixture the components of the mixture interact to form a microfoam.
Claims20
A method of treating a patient in need of sclerotherapy of a blood vessel, comprising:
- administering a microfoam from a device, the device comprising:
- a housing in which is situated a pressurisable chamber containing a solution comprising at least one sclerosing agent in a physiologically acceptable solvent;
- a pathway with at least one outlet orifice by which the solution may pass from the pressurisable chamber to an exterior of the device through the at least one outlet orifice;
- and
- a mechanism by which the pathway from the pressurisable chamber to the exterior can be opened or closed such that, when the pressurisable chamber is pressurised and the pathway is open, fluid will be forced along the pathway and through the at least one outlet orifice;
- wherein the housing includes an inlet for the admission of a pressurised source of physiologically acceptable gas that is dispersible in blood, the physiologically acceptable gas being in contact with the solution upon activation of the mechanism to produce a gas-solution mixture,
- wherein the pathway to the exterior of the housing includes at least one foaming element, and
- wherein the physiologically acceptable gas that is dispersible in the blood is stored in a container provided with engaging means for engaging with the housing holding the solution comprising the at least one sclerosing agent,
- and wherein the solutions is stored in the presence of at least one inert gas.
6 more elements
A method of treating a patient in need of sclerotherapy of a blood vessel, comprising:
- administering to the blood vessel a microfoam from a device, the device comprising:
- a housing in which is situated a pressurisable chamber containing a solution comprising at least one sclerosing agent in a physiologically acceptable solvent;
- a pathway with at least one outlet orifice by which the solution may pass from the pressurisable chamber to an exterior of the device through the at least one outlet orifice;
- a mechanism by which the pathway from the pressurisable chamber to the exterior can be opened or closed such that, when the pressurisable chamber is pressurised and the pathway is open, fluid will be forced along the pathway and through the at least one outlet orifice;
- and
- a pressurised container containing a physiologically acceptable blood-dispersible gas;
- wherein the housing includes an inlet for the admission of the blood-dispersible gas, the gas being in contact with the solution upon activation of the mechanism to produce a gas-solution mixture,
- and wherein the solution is stored in the presence of at least one inert gas.
5 more elements
Dependencies are inferred from the claim text.