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US 7,819,796 B2Granted
Embryo modification and implantation
AssigneeKode Biotech Limited
InventorsDeborah A. Blake, Nicola L. Carter, Stephen M. Henry
Life of this patent
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Abstract
The present invention relates to constructs and methods used to enhance the attachment and implantation of an embryo. It is shown that modified glycolipids and glycolipid-attachment molecule constructs can be used to modify embryos, or localised to target tissues, to enhance interaction between the embryo and the target tissue, (typically the endometrium). The invention may advantageously be used to enhance implantation of embryos in the uterus, for example, in IVF treatments.
Claims32
A method of enhancing the implantation of an embryo into the endometrium of an animal including the steps:
- a. modifying the embryo to incorporate a glycolipid-attachment molecule construct;
- and
- b. transferring the modified embryo to the uterus of the animal;
- where a glycolipid is exogenously modified to incorporate a binding part adapted to enable the modified glycolipid to bind the attachment molecule.
1 more element
Dependencies are inferred from the claim text.