Estrogenic extracts of Morus alba and uses thereof
AssigneeBionovo, Inc.
InventorIsaac Cohen
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Abstract
Extracts of various species of the Moraceae family have estrogenic properties. For example, aqueous and ethanolic extracts of Morus alba L. species possess estrogenic properties in both ERα+ and ERβ+ cells. These estrogenic effect include estrogen response element (ERE) stimulation as well as tumor necrosis factor (TNF) repression. Methods are provided for treating climacteric symptoms, breast and/or uterine cancer, and osteoporosis.
Claims5
A method of eliciting an estrogenic effect in a post-menopausal female patient in need of such estrogenic effect, comprising administering to the post-menopausal female patient an estrogenically effective amount of a pharmaceutical composition comprising an extract from the leaves of Morus alba L, wherein the estrogenic effect includes treating at least one climacteric symptom.
Dependencies are inferred from the claim text.